The Uveal Tract Overview
The uveal tract (also called the uvea) is the eye's vascular middle layer, sandwiched between the outer fibrous tunic (sclera/cornea) and the inner nervous tunic (retina). It is the eye's primary blood supply network and has three continuous components:
- Iris (anterior)
- Ciliary body (middle)
- Choroid (posterior)
All three share a continuous blood supply and are derived from the same embryological tissue, which is why inflammation in one part often affects the others (uveitis).
The Choroid
The choroid is the largest component of the uveal tract, extending from the ora serrata anteriorly to the optic nerve posteriorly. It lies between the sclera (outside) and the retinal pigment epithelium (inside).
Structure
The choroid has four main layers (outer to inner):
- Suprachoroidal space: A potential space between choroid and sclera containing loose connective tissue
- Large vessel layer (Haller's layer): Contains large arteries and veins
- Medium vessel layer (Sattler's layer): Contains medium-sized blood vessels
- Choriocapillaris: A dense capillary network immediately adjacent to the RPE
Beneath the choriocapillaris lies Bruch's membrane, a thin layer separating the choroidal vasculature from the RPE.
Functions of the Choroid
- Nourishes the outer retina: The choriocapillaris provides oxygen and nutrients to the photoreceptors and RPE (the inner retina is supplied by the central retinal artery)
- Absorbs scattered light: Melanocytes in the choroid absorb stray light, reducing reflections that would degrade image quality
- Temperature regulation: The extremely high blood flow (the highest per gram of any tissue in the body) helps dissipate heat from light absorption by the RPE
- Uveoscleral outflow: Provides a secondary pathway for aqueous humor drainage
The Ciliary Body
The ciliary body extends from the iris root to the ora serrata. It has two main parts:
- Pars plicata: The anterior, folded portion containing the ciliary processes that produce aqueous humor
- Pars plana: The posterior, flat portion. A common surgical entry point because it lacks critical structures
Functions
- Aqueous humor production by the ciliary processes
- Accommodation via the ciliary muscle, which controls zonular tension on the crystalline lens
- Zonular fiber anchor: The zonules of Zinn extend from the ciliary body to the lens equator
The Iris
The iris is the most anterior component of the uveal tract. It is the colored, visible diaphragm that controls the pupil aperture. Its anatomy and function are covered in detail in the Iris & Pupil Function topic.
Uveitis: When Things Go Wrong
Inflammation of the uveal tract is called uveitis, and it is classified by location:
| Type | Location | Common Signs |
|---|---|---|
| Anterior uveitis (iritis) | Iris and anterior ciliary body | Pain, redness, photophobia, miosis |
| Intermediate uveitis | Ciliary body and peripheral retina | Floaters, blurred vision |
| Posterior uveitis (choroiditis) | Choroid | Blurred vision, floaters, visual field loss |
| Panuveitis | All three structures | Combined symptoms |
Key Takeaways
- The uveal tract has three parts: iris, ciliary body, and choroid
- The choroid nourishes the outer retina and has the highest blood flow per tissue weight
- The ciliary body produces aqueous humor and controls accommodation
- All three components share blood supply, so inflammation can spread (uveitis)
- The choriocapillaris and Bruch's membrane are the interface between choroid and RPE